Pleural effusion occurs when excess fluid accumulates between the layers of the pleura surrounding the lungs. It can be caused by infections, heart failure, or cancer. Dr. Mayank explains that symptoms include shortness of breath, chest pain, and a dry cough. Diagnosis is made through chest X-rays or ultrasound. Treatment options include draining the fluid via thoracentesis or addressing the underlying cause. If left untreated, pleural effusion can lead to lung collapse or respiratory failure.